We sponsored a pre-accelerator summer school with the aim of supporting companies moving on to the full 8-week KQ Lab accelerator programme. You can read a case study of one of the companies that came through this programme here.
Strategic Projects
The UK SPINE supports initiatives which we have identified as essential to the KE needs of the UK SPINE network. These projects are conceptualised, initiated and run in collaboration with our strategic partners.
Data Science X Biomedical Science Summer School with KQ Labs, Entrepreneurs First, the Alan Turing Institute, and the Francis Crick Institute
Project lead:
Barbara Domayne-Hayman, The Francis Crick Institute
A Roadmap of Current Needs in Drug Discovery for Healthy Ageing
Project lead:
Graeme Wilkinson, Medicines Discovery Catapult
This project, led by the Medicines Discovery Catapult, will deliver a translational roadmap for developing drugs for aging. This will provide guidance of the route from early stage translation to commercialisation/clinical implementation.
Evaluation of epigenetic targets in ageing
Project lead:
Panagis Filippakopoulos, University of Oxford
The goal of this project is to establish novel epigenetic targets in ageing that can potentially engage single target/multiple pathway & multiple morbidity nodes. This is done through bioinformatic meta-analysis of targets for both existing and novel pharmaceutical assets that have been developed by the Structural Genomics Consortium. Subsequently, the aim will be to translate these molecules in the UK SPINE drug discovery pipeline.
High risk target identification in age-related multimorbidity
Project lead:
Clare West, University of Oxford
The goal of this early bioinformatics target discovery project is to identify underexplored drug targets that have the potential to create a step change in treating multiple age-related diseases and multimorbid traits. This is done by combining valuable high throughput information generated by the Structural Genomics Consortium, UK SPINE consortium and the Open Targets public-private initiative.
The Impact on NHS Costs of Delaying the Onset of Multi-morbidity in Old Age (INCDOM)
Project lead:
Stuart Redding, Centre for Health Services, Economics and Organisation, University of Oxford
This project will provide hypothetical and indicative estimates of cost savings that may be achieved if the onset of multiple morbidities in old age can be delayed by the development of new hypothetical treatments.